Skip to content

Human brains are getting larger each decade. That's the conclusion of researchers conducting the large Framingham Heart study which has now gone on for 75 years.

Between 1999 and 2019 the researchers conducted MRIs on participants born from the 1930s to the 1970s, with participants having an average age of 57. They found that each decade the brain volume steadily increased, with the brains of people born in the 1970s having 6.6% more volume than those born in the 1930s. Brain surface area increased about 15% in that time.

Brain structures such as white matter, gray matter, and hippocampus (a brain region involved in learning and memory) also increased in size over time. This increase in brain volume clearly shows that environmental factors (e.g., nutrition, education, social), and not just genetic factors, influence brain size.

The researchers thought that a larger brain volume, which signifies brain health,  might be protective against Alzheimer's disease. And that this could explain why the percentage of people (the incidence) of Alzheimer's disease and dementia has gone down over time.

From Medical Xpress: Human brains are getting larger: That may be good news for dementia risk

A new study by researchers at UC Davis Health found human brains are getting larger. Study participants born in the 1970s had 6.6% larger brain volumes and almost 15% larger brain surface area than those born in the 1930s. ...continue reading "Human Brains Are Getting Larger Over Time"

It turns out that some commonly found chemicals in household products are actually hazardous to our brain health. A recent study found that these chemicals have a harmful effect on brain cells called oligodendrocytes. The harmful chemicals are quaternary compounds (found in some disinfectant products and personal care products) and some flame retardants found in household items such as furniture and electronics.

Oligodendrocytes are cells in the central nervous system that form the myelin sheath (a layer that covers and protects nerve cells) in the brain and spinal cord. Damage to the myelin sheath underlies some neurological diseases, such as multiple sclerosis.

The researchers felt that exposure to these chemicals that damage oligodendrocytes may be a risk factor for neurological diseases. In other words, you don't want to damage these cells. Pregnant women (developing baby) and children (developing brains!) are especially vulnerable.

Bottom line: Avoid disinfecting or cleaning supplies that say they contain "quaternary compounds" and try not to buy products containing flame retardants. Check labels!

From Science Daily: Common household chemicals pose new threat to brain health, study finds

A team of researchers from the Case Western Reserve University School of Medicine has provided fresh insight into the dangers some common household chemicals pose to brain health. They suggest that chemicals found in a wide range of items, from furniture to hair products, may be linked to neurological conditions like multiple sclerosis and autism spectrum disorders. ...continue reading "Some Common Household Chemicals Have A Harmful Effect On the Brain"

Chronic wasting disease is slowly spreading through the US - county by county, state by state. In July 2022 it had been detected in deer, moose, or elk in 30 states, and by December 2023 in 32 states.

In December 2023, it was detected in Kentucky in a white-tailed buck that a hunter killed. Chronic wasting disease (CWD) has now been found in deer in 6 of the 7 states bordering Kentucky. [CDC map]

Chronic wasting disease is an always fatal neurologic disease that can occur in cervids (deer, elk, moose, reindeer). It is a prion disease similar to "mad cow disease" (bovine spongiform encephalopathy) in cattle and Creutzfeldt-Jakob's disease in humans. There is no vaccine, treatment, or cure for the disease.

So far there is no evidence that CWD has crossed over to humans. But extra caution should be taken. Don't eat meat from infected deer or moose. Hunters should follow state precautions in field dressing and butchering, and have the meat tested for CWD. [CDC site for CWD]

How is it spread? Scientists believe CWD prions spread between animals through body fluids (e.g., feces, saliva, blood, or urine), either through direct contact or indirectly through environmental contamination of soil, food or water. Once introduced into an area or farm, the CWD prion (protein) is contagious within deer and elk populations and spreads.

Once CWD gets into the soil, it stays there for years, and so animals can contract it even after infected deer and elk have died. Recent research found that plants uptake the prions where it remains infectious. Yikes!

How do you get rid of it? Unfortunately, high heat, disinfectants, and radiation don't kill the CWD prions. Dr.Zabel at the Colorado State Univ. Prion Research Center suggested a few years ago that controlled burns (fires) of infected fields or areas could eliminate the prions left behind by infected animals (from animal mucus/saliva, urine, and feces, and decaying carcasses) on plants and soil.

A concerning study. From Center for Infectious Disease Research and Policy (CIDRAP) : Plants can take up CWD-causing prions from soil in the lab. What happens if they are eaten? ...continue reading "Chronic Wasting Disease Now Detected In 32 States"

Credit: Wikipedia

Cancer tumors have a different microbiome (community of microbes) than healthy tissue. Researchers have been finding the bacteria Fusobacterium nucleatum (F. nucleatum) in a number of cancers, with high levels of its presence associated with a poorer outcome for the person (more metastases and death).

A recent study found that one strain or subtype of  F. nucleatum (called Fna C2)  is found in tumors of about 50% of aggressive colon cancers.

Interestingly, F. nucleatum is a normal oral bacteria - one found in the mouth of people, and also associated with periodontal disease. It is rarely found in the gastrointestinal (GI) tract of healthy persons.

It is thought that the bacteria somehow travels from the mouth to the stomach, where it can withstand stomach acid, and then grows there in the gastrointestinal tract. F. nucleatum is cancer promoting - for example, it has a supporting role in tumor progression. It appears to be resistant to cancer treatments.

Researchers are now wondering if certain beneficial or good bacteria ingested by the person or somehow delivered to the tumor site  can battle the F. nucleatum, perhaps as part of cancer therapy. Stay tuned....

From Science Daily: Bacteria subtype linked to growth in up to 50% of human colorectal cancers

Researchers at Fred Hutchinson Cancer Center have found that a specific subtype of a microbe commonly found in the mouth is able to travel to the gut and grow within colorectal cancer tumors. This microbe is also a culprit for driving cancer progression and leads to poorer patient outcomes after cancer treatment. ...continue reading "A Specific Bacteria and Colorectal Cancer"

It has been known for a while that getting a good night's sleep after getting vaccinated results in a stronger immune response. Twice as strong response! A recent study suggests that this could be due to beneficial T-cells (which are part of immune system) migrating toward the lymph nodes during sleep.

Growth hormone and prolactin are both involved in the migrating response.

Similarly, many studies find that having a short sleep duration (less than 6 hours) after a vaccination reduces the immune antibody response.

Bottom line: If you want a good antibody/immune response to a vaccine - get a good night's sleep of 6 or more hours after being vaccinated! Good sleep stimulates the immune system.

From Science Daily: Immunology: Good sleep stimulates the immune system

Sleep is healthy -- this popular knowledge is backed by science.

Previous research had already shown that in people who slept after a vaccination, the immune response was twice as strong on average as in people who did not sleep during the night after the vaccination. However, the cell biological reasons for this had been little investigated before now.

...continue reading "Get A Good Night’s Sleep After Getting Vaccinated"

After reports that life expectancy for Americans was down in 2021, the CDC (Centers for Disease Control and Prevention) just released a report that in 2022 the life expectancy has once again increased.

The key finding in the report was that life expectancy for the U.S. population in 2022 was 77.5 years. This is an increase of 1.1 years from 2021. It increased for both males and females in 2022, but there is still a life expectancy gap between them. For males, life expectancy increased 1.3 years from 2021 to 74.8 in 2022. For females, life expectancy increased 0.9 year to 80.2 in 2022.

Heart disease and cancer remain the top 2 causes in 2022 (same as in 2021), while deaths from COVID-19 dropped from #3 in 2021 to #4. "Unintentional injuries" (e.g., accidents, drug overdose, homicide) is now #3 (it was #4 in 2021).

Excerpts from the CDC NCHS Data Brief No. 492, March 2024: Mortality in the United States, 2022 (pdf version) and the CDC page: Mortality in the United States, 2022

Key findings - Data from the National Vital Statistics System
  • Life expectancy for the U.S. population in 2022 was 77.5 years, an increase of 1.1 years from 2021.

...continue reading "Life Expectancy For US Population Increased in 2022"

Women have been outliving men for more than a hundred years. But a recent study found that this gap in life expectancy has been widening for more than a decade. This gap is now 5.8 years. Life expectancy (combined for both men and women) was 78.8 years in 2019 (pre-Covid 19), but was 76.1 years in 2021.

Why is this gap widening? The main reasons for men's life expectancy decreasing are Covid-19 and opioid overdoses. Other reasons are suicide, accidents (unintentional injuries), heart disease, and alcoholic liver disease.

On the other hand, the gap may be shrinking since the development of Covid vaccines and better treatments, as well as widely available overdose treatments (Naloxone).

From Science Daily: US men die 6 years before women, as life expectancy gap widens

We've known for more than a century that women outlive men. But new research led by UC San Francisco and Harvard T.H. Chan School of Public Health shows that, at least in the United States, the gap has been widening for more than a decade. The trend is being driven by the COVID-19 pandemic and the opioid overdose epidemic, among other factors. ...continue reading "Life Expectancy Gap Between Men and Women Is Widening"

There may be new treatments on the horizon for the most aggressive and deadly brain cancer known as glioblastoma. The median survival is less than one year, so this is very exciting news.

Two studies, using slightly different approaches, were tested on a very small number of patients (3 in one study, 6 in the other). Both approaches used the patient's own modified T-cells (part of immune system) to attack the brain tumor. Initially there was amazing shrinkage of the tumors, but unfortunately this effect was only temporary for most.

The ultimate goal is to make treatments that have long-lasting effects. By the way, glioblastoma is the brain cancer that killed President's son Beau, as well as Arizona Senator John McCain.

[Click on the article link to see amazing MRI scan images of brain tumor shrinkage.] From Medical Xpress: A new strategy to attack aggressive brain cancer shrank tumors in two early tests

Scientists took patients' own immune cells and turned them into "living drugs" able to recognize and attack glioblastoma. In the first-step tests, those cells shrank tumors at least temporarily, researchers reported Wednesday. ...continue reading "Promising New Approach For Treating Deadly Brain Cancers"

Lead is harmful, especially for children. Lowered IQ, learning disabilities, behavioral problems - all from lead exposure. There are no safe lead levels in individuals, so you want to avoid lead and lead-containing products whenever possible. So it shouldn't be a surprise that a study found that owning guns (firearms) is correlated with elevated lead levels in children.

The cause is the lead ammunition (bullets) and primer used in the firearms. Lead styphnate is commonly used in the primer, which is the explosive that ignites the gunpowder. When a bullet is fired, fumes and fine lead particles are released into the air.

The researchers point out: When lead bullets are used, and the guns are discharged, then lead dust is produced. This lead dust gets everywhere, including on clothes, the body, personal items (e.g., phone, bags, laptop), and in vehicles. The lead dust is brought home, where it further settles on toys, the floor, rugs, and upholstery.

By the way, for hunters bringing home meat they killed with lead bullets - the lead (from tiny fragments or microscopic pieces) gets into the meat far from the bullet. So they are eating meat contaminated with lead. And the more of this meat is eaten, the higher the blood levels in the person.

Bottom line: Use non-lead bullets in firearms. 

From Science Daily: Firearm ownership is correlated with elevated lead levels in children, study finds

Childhood lead exposure, primarily from paint and water, is a significant health concern in the United States, but a new study has identified a surprising additional source of lead exposure that may disproportionately harm children: firearms. ...continue reading "Firearms and Elevated Lead Exposure In Children"

The studies finding health harms from ultra-processed foods keep coming. Ultra-processed foods are food products manufactured with all sorts of ingredients (additives) not normally found in our kitchens. Examples of such ingredients are: emulsifiers, carrageenan, mono- and diglycerides, soy lecithin, polysorbate, cellulose, colors, titanium dioxide, high fructose corn syrup, hydrogenated oils, dextrose, whey protein, nitrates, flavors (artificial and natural), colors, etc.

A large review of studies (none of which were affiliated with companies producing ultra-processed foods) found that eating ultra-processed foods are linked to over 30 health harms. Some of the health harms had especially strong associations: early death, death from heart disease (cardiovascular disease), type 2 diabetes, adverse sleep outcomes, wheezing, and obesity. In general, the more ultra-processed foods one ate, the higher the risk for harms.

Bottom line: Read ingredient lists, and try to avoid ultra-processed foods. Even foods such as cereals can have one that is ultra-processed (a formulation of ingredients that result from industrial processes) next to one that only has natural real ingredients without any additives.

From Medical Xpress: Consistent evidence links ultra-processed food to over 30 damaging health outcomes

Consistent evidence shows that higher exposure to ultra-processed foods is associated with an increased risk of 32 damaging health outcomes including cancer, major heart and lung conditions, mental health disorders, and early death. ...continue reading "Over 30 Health Harms Associated With Ultra-Processed Foods"